Laboratory Infrastructure, SoBT

The Central MassArray Facility at SMVDU represents a landmark achievement in the state of Jammu and Kashmir, distinguishing itself as a pioneering laboratory not only within the state but also across Northern India. This facility is equipped with the Agena MassArray Analyzer System (formerly known as Sequenom), a highly sophisticated and robust technology renowned for its accuracy and wide-ranging applications in the scientific community. The MassArray system is employed for critical research and diagnostics, including the detection of genetic diseases, pathogen identification, the advancement of personalized medicine, and contributions to agricultural, veterinary, and microbial genomics. The establishment of such a facility underscores SMVDU’s dedication to enhancing its research infrastructure, thereby fostering significant scientific advancements and innovation in the region. It highlights the institution’s role in pushing the boundaries of research and technology, making significant contributions to healthcare, agriculture, and biotechnology, and promoting the growth of scientific knowledge and applications in Northern India.

The laboratory serves as a research hub for various fields, including Metagenomics, Genomics, and DNA fingerprinting of plants. It supports interdisciplinary research work and currently hosts two full-time research scholars. The infrastructure of the laboratory is well-equipped with cutting-edge technology, including the latest gel electrophoretic systems of various sizes, a gel documentation system for visualizing and documenting gels, a -200°C deep freezer for sample storage, and a fully computerized double beam UV-Visible spectrophotometer for precise spectroscopic analysis. In addition, the laboratory is equipped with various other essential instruments such as temperature-controlled water baths, vortex shakers, and gel rockers. This comprehensive range of equipment allows researchers to carry out advanced experiments and analysis, fostering innovation and progress in the field of molecular biology and genomics.

This spacious laboratory is meticulously equipped with an array of sophisticated equipment designed to support extensive research in metabolite production from microbial biomass. Among its key instruments are high-precision microscopes for detailed cellular studies, an incubator shaker for culturing and maintaining microbial cultures under controlled conditions, and a single-beam spectrophotometer for measuring the absorbance of various samples. The laboratory also features a laminar air flow cabinet to ensure a sterile environment for sensitive experiments. A highlight of this facility is the fully computerized lab-scale Fermentor (Sartorius), which allows for precise control over fermentation processes. Additionally, an advanced, fully computerized Gas Chromatography system is available for the accurate analysis of chemical compounds in the microbial biomass. This comprehensive setup enables researchers to explore and innovate in the field of biotechnology, specifically focusing on the efficient production of valuable metabolites from microorganisms.

The bioinformatics centre, a cornerstone of technological excellence, is fully equipped with a dedicated server, 30 high-performance computers, and an exclusive 4 Mbps internet connection, ensuring high-speed data processing and online research capabilities. The lab is further enhanced by the latest software installed on four advanced workstations, specifically dedicated to pioneering research in the realms of molecular modelling, in-silico drug design, and molecular graphics. This state-of-the-art setup facilitates a cutting-edge research environment, enabling scientists and researchers to delve deeply into complex biological systems, simulate molecular interactions, and design novel therapeutic agents. The centre’s comprehensive resources support a wide range of bioinformatics projects, from theoretical computational studies to practical applications in drug discovery, making it a vital hub for innovation and development in the field.

This advanced laboratory, meticulously constructed based on the latest design principles, fully caters to the comprehensive needs of contemporary tissue culture research. It operates as a full-time research facility, primarily focusing on micropropagation and the production of plant metabolites with significant pharmacological properties. The laboratory is furnished with cutting-edge equipment, including the latest laminar air flow chambers, incubator shakers, and a highly specialized plant growth room. This room is designed to precisely control light, humidity, and temperature conditions, creating an optimal environment for plant growth and experimentation. Such facilities enable the lab to pioneer in the cultivation of plants under controlled conditions, facilitating groundbreaking research in plant science, pharmacology, and biotechnology. This lab represents a significant stride forward in the field, offering unparalleled resources for the development of new pharmaceuticals and agricultural innovations.

The Organic Chemistry laboratory is a fully equipped facility designed to support a wide range of experiments, catering both to advanced research initiatives and the educational requirements of the school curriculum. This lab is at the forefront of exploring enzyme-mediated organic synthesis and biotransformation, showcasing the integration of biological processes in chemical synthesis. It houses an array of specialized equipment, including reflux chambers for conducting prolonged heating under reflux, precise titration apparatus for quantitative analysis, and temperature-controlled water baths essential for maintaining specific reaction conditions. These tools are critical for experiments that require exacting standards of temperature and environmental control, making this laboratory a vital resource for students and researchers alike. The laboratory’s commitment to providing comprehensive infrastructure underscores its role in fostering innovation and education in organic chemistry, enabling significant advancements in research and offering students practical, hands-on experience in the field.

The basic biotechnology laboratory is a cornerstone for school curriculum laboratory work, specifically designed to support the intricate studies of biochemistry, immunology, and bioprocess engineering. This laboratory stands out for its modern and sophisticated instrumentation, aimed at providing students with a comprehensive hands-on experience. Among its notable equipment, the BOD (Biochemical Oxygen Demand) incubator facilitates precise cultivation conditions for microorganisms. A Windows-operated pH meter ensures accurate measurement of acidity or alkalinity. The fully computerized double beam spectrophotometer allows for detailed analysis of chemical substances, while the Gel Electrophoresis units are crucial for the separation and analysis of proteins and nucleic acids. This lab is not only a hub for learning and discovery but also a testament to the commitment to equip future scientists with the knowledge and tools necessary for advancing in the field of biotechnology.

The microbiology laboratory is specifically designed to support undergraduate students’ laboratory work, with a current focus on research in Bioethanol production. This state-of-the-art facility is well-equipped with the latest technology, including advanced microscopes for detailed microbial examination, a fume-hood to ensure a safe working environment by extracting hazardous fumes, and an autoclave facility for the sterilization of equipment and media used in experiments. These tools and facilities are essential for conducting a wide range of experiments, allowing students to gain hands-on experience in microbiology research and techniques, thereby fostering a practical understanding of Bioethanol production processes.

This fundamental molecular biology laboratory is dedicated to conducting DNA manipulation work as part of the school curriculum, offering students a hands-on learning experience in the field of genetic engineering. Additionally, the laboratory provides comprehensive support for student-led investigational projects, specifically focusing on gene cloning for various target genes. This educational facility is designed to introduce students to the practical aspects of molecular biology, including DNA extraction, amplification, sequencing, and manipulation techniques. By engaging in these projects, students gain invaluable insights into the complexities of genetic engineering, preparing them for future studies and careers in biotechnology, genetics, and related fields. The laboratory serves as a crucial educational resource, fostering curiosity, critical thinking, and technical skills among students, thereby contributing to the advancement of scientific knowledge and innovation.

The Indian Council of Medical Research (ICMR) lab at Shri Mata Vaishno Devi University represents a significant advancement in the field of medical research and diagnostics within the region. This facility is equipped with state-of-the-art technology and infrastructure to conduct advanced research in various medical domains. It aims to foster innovation, develop new diagnostic methods, and contribute to the global body of medical knowledge. The collaboration with ICMR elevates the university’s capabilities in contributing to critical health challenges, offering students and researchers unparalleled opportunities to work on groundbreaking projects. This lab not only enhances the university’s research portfolio but also plays a crucial role in improving public health outcomes.